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An extracranial medical device for photobiomodulation
Extra-cranial infrared photoillumination offers hope for Alzheimer's disease
It is a flexible support system that fits an adult's head. It integrates an embedded battery and about sixty infrared LEDs emitting at 810 nm, whose illumination sequences can be programmed in terms of duration and frequency.
It complies with the specifications of the IEC 60601 standard and can be used for clinical trials to evaluate the impact of extra-cranial infrared illumination for neurodegenerative pathologies, including Alzheimer's disease.
The trials are performed in a medical setting. The fact that the system does not require an external power supply strongly limits the discomfort for patients, both day and night.
Clinical trials for various pathologies or areas of research:
• Alzheimer's disease
• Lewy body disease
• San Filippo disease
• Cranial trauma: to identify new markers that can help track the severity or evolution of a situation
• Cognitive disorders: depression, bipolarity, obsessive-compulsive disorders (OCD)
• M. Dole, V. Auboiroux, L. Langar,
J. Mitrofanis. “A systematic review
of the effects of transcranial
brain activity in humans”. Rev
Neurosci. 2023 Mar 17. doi: 10.1515/
ahead of print. PMID: 36927734.
• K. Xie, H. El Khoury, J.
Mitrofanis, PJ. Austin(2022)
“A systematic review of the
effect of photobiomodulation
on the neuroinflammatory
response in animal models of
Reviews in Neurosciences doi:
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.